Admin accounts are the highest-value target in any Microsoft 365 environment. A single compromised Global Admin or Exchange Admin can reconfigure the entire tenant — disabling security controls, creating backdoor accounts, exfiltrating data, or handing over persistent access to an attacker — without ever triggering an alert. Yet many organisations still rely on passwords alone for privileged accounts, or apply MFA inconsistently across their admin population.
Microsoft's own data shows that MFA blocks over 99% of account compromise attacks. For admin accounts specifically, the consequence of skipping this control isn't a single compromised inbox — it's the entire tenant. A policy that requires strong MFA specifically for administrator roles is one of the most important security baselines you can put in place.
Note that "strong MFA" for admins means more than SMS or voice call. Phishing-resistant methods — FIDO2 security keys or certificate-based authentication — are the recommended standard. At minimum, Microsoft Authenticator with number matching should be enforced for all privileged identities.
There are very few legitimate exceptions to MFA for admin accounts:
An exclusion that exists without documentation or a named owner is not a break-glass account. It is a gap.
After enforcing this control, review these related areas: